3D Bio-Tisssues

3D Bio-Tissues (3DBT) is a biotechnology company that specializes in tissue engineering through its proprietary tissue templating platform. Spun out from Newcastle University in 2019 and now a subsidiary of BSF Enterprise, the company employs a bottom-up, bio-inspired manufacturing approach to generate structured, functional, and scalable tissues. By utilizing cellular processes rather than artificial scaffolds, the company creates products that replicate natural hierarchical structures at both nano- and macro-scales. Their technology also incorporates macromolecular crowders—media additives designed to mimic the natural physiological environment—which help accelerate cell growth while reducing operational costs and avoiding animal-derived components.

The company's work addresses critical needs in clinical applications and cellular agriculture by providing sustainable, high-performance alternatives to traditional materials. Key focus areas include the development of lab-grown meat, which aims to achieve texture and bite parity with conventional products; bio-engineered human cornea for medical devices; and lab-grown leather that mimics the collagen fiber structure of animal skin. By enabling the production of these complex tissues in a scalable, animal-free format, 3D Bio-Tissues seeks to improve patient outcomes and transform sustainable manufacturing across fashion, food, and biopharmaceutical industries. Proof of their technical progress includes achieving the world's first 100% lab-grown pork fillet and developing leather that complies with professional microscopy standards for natural leather.