amofor GmbH provides in-silico drug formulation services and software, leveraging thermodynamic modeling to predict physical stability. It helps the pharmaceutical industry reduce trial-and-error in developing stable, bioavailable formulations.
amofor GmbH is a German biotechnology and pharmaceutical services company that provides in-silico drug formulation development and proprietary software tools. Founded as a spin-off from TU Dortmund University, the company utilizes physical chemistry and thermodynamic modeling—specifically the PC-SAFT framework—to predict the physical stability of active compounds. Their offerings include digital formulation services for amorphous solid dispersions, salt forms, and cocrystals, alongside their flagship software, SolCalc. By applying physics-based computational models, amofor enables researchers to screen excipients and determine optimal manufacturing methods, such as spray drying or hot-melt extrusion, before physical experiments begin.
This methodology is designed to replace traditional trial-and-error approaches in pharmaceutical development, helping clients reduce lab time and material costs while increasing development efficiency. By providing both specialized software and expert consulting, amofor addresses critical challenges in drug stability and bioavailability. The company serves the pharmaceutical, agrochemical, and life science sectors, aiming to streamline the transition from early-stage conceptualization to market-ready products with scientifically rigorous, predictive modeling. Their expertise in thermodynamics assists developers in managing complex mixtures and optimizing the long-term performance of formulated molecules.