Biointerphase Incorporated

BioInterphase is a mission-driven bioengineering studio based in Pittsburgh, Pennsylvania, that focuses on biomaterials and biosignals intelligence. Founded in 2015, the company designs, develops, and demonstrates sustainable technologies to improve the interaction between critical hardware and the environment. Its core product offerings include THERMOPHASE, a biocide surface treatment technology that creates a single-molecule monolayer on hardware to enhance heat transfer efficiency while preventing organic and inorganic fouling. Additionally, the company has developed INTELLIPHASE, an artificial intelligence and machine learning technique designed to predict chiller fouling and optimize energy efficiency in industrial cooling systems.

These solutions are engineered to serve industries that rely on advanced cooling and environmental performance, such as power plants, defense, HVAC, and energy generation. By creating a more seamless and efficient interface between technology and the world, BioInterphase aims to restore and reinforce biological needs while reducing operational waste. The company operates as a research-focused organization that utilizes sustainable engineering practices to create impactful products, backed by various federal grants and research partnerships to steward its technologies into practical industrial applications.