ENDOBIOS Biotech

ENDOBIOS Biotech is a Lisbon-based company focused on the discovery and development of bioactive natural products from microorganisms. The company has developed proprietary, high-throughput screening technologies that trigger the production of cryptic or silent natural compounds found within the genomes of bacteria, fungi, and microalgae. By using custom induction keys, ENDOBIOS activates these hidden chemical scaffolds, which have been refined through evolution but typically remain dormant in standard laboratory culture conditions. Additionally, the company is a pioneer in the application of endosymbiotic bacteria, utilizing its specialized knowledge to explore new biological traits for therapeutic and diagnostic use.

These proprietary platforms and methods are applied to drug discovery in fields such as infectious diseases, including the development of new antibiotics, and neuropathies, specifically targeting epilepsy and pain relief. Beyond its in-house research and development pipeline, which includes candidates like ENB-001 for CNS disorders, ENDOBIOS provides specialized consulting and R&D services to partners in the pharmaceutical, agricultural, and cosmetic sectors. These services include microbial isolation, bioassay development, and the implementation of cost-effective, high-throughput screening facilities, allowing clients to accelerate their own discovery pipelines and optimize natural product research.