Helix Biostructures

Helix BioStructures is an Indianapolis-based contract research organization (CRO) founded in 2017 that provides integrated, gene-to-structure services for the biopharmaceutical and agricultural biotechnology industries. The company specializes in early-stage drug discovery, offering comprehensive expertise in recombinant protein production, biophysical characterization, and advanced structural biology techniques including X-ray crystallography, cryo-electron microscopy (cryo-EM), and Small-Angle X-ray Scattering (SAXS). By utilizing a flexible co-sourcing model, Helix provides partners with access to state-of-the-art analytical technologies and scientific expertise, helping clients accelerate their research by optimizing protein quality and elucidating complex structural mechanisms essential for therapeutic and agricultural development.

These services are critical for organizations navigating the complexities of drug design and agricultural crop protection. Helix supports clients by managing the end-to-end process from gene construct design and expression to the high-throughput structural analysis required for validating drug candidates. Their work has been instrumental in helping research teams achieve high-impact scientific publications and meet regulatory standards. With a team of experienced protein biochemists and structural biologists, the company is recognized for its ability to deliver challenging structural data on time and under budget, effectively serving as an extension of their partners' internal research and development teams to solve complex biological problems.