Insilica

Insilica is a bioinformatics company that provides a scientific intelligence platform designed to automate evidence synthesis and regulatory-grade risk assessments for toxicological and chemical safety applications. The company has developed an integrated system comprised of three interconnected products: BioBricks, which serves as a FAIR-compliant data infrastructure containing curated toxicology datasets; ToxIndex, which uses agentic orchestration to transform chemical inventory queries into complete regulatory artifacts, such as OEL/HBEL reports and REACH dossiers; and Sysrev, a platform that facilitates human-in-the-loop expert validation to ensure accuracy and generate the auditable trails required for regulatory submissions.

This technology is intended to assist toxicologists, regulatory agencies, and pharmaceutical companies by significantly reducing the time spent on manual data retrieval and report generation. By combining AI-powered extraction with expert oversight, the platform addresses high-stakes literature review and safety assessment challenges that traditionally take months to complete, enabling more efficient decision-making processes. Insilica’s work is supported by research grants from institutions like the National Institutes of Health (NIH) and the National Science Foundation (NSF).