MHCombiotic Inc.

MHCombiotic Inc. is a Calgary-based biotechnology company focused on developing antimicrobial solutions to combat antimicrobial resistance (AMR), biofilms, and chronic infections. The company utilizes a proprietary technology platform to create novel, biocompatible antibacterial agents. Its pipeline includes medical devices, such as the ComBatic™ antimicrobial wound care line, as well as therapeutics for respiratory infections and systemic conditions like sepsis. The technology works by integrating multi-omics characterization and large-scale formulation screening—having screened over 18,000 combinations—to deliver broad-spectrum treatments that mitigate inflammation, oxidative stress, and bacterial proliferation.

These innovations address critical global health challenges, serving sectors including clinical wound care, respiratory health, and specialized environments such as combat casualty care. By focusing on non-toxic, biofilm-eradicating therapies, the company aims to improve patient outcomes, reduce the burden on healthcare systems, and provide effective alternatives to traditional treatments for drug-resistant pathogens. MHCombiotic advances its candidates through preclinical validation and regulatory pathways in collaboration with academic institutions and clinical partners, supported by international patents and industry-recognized awards in antimicrobial innovation.