MVT in Silico

MVT in Silico is a life sciences R&D company that specializes in physiologically based computer modelling and simulation to support drug and drug-device combination development. The company has developed the MVT Physiology Engine, a cyber-physical, indication-agnostic platform designed to provide human-relevant pharmacometrics. By leveraging computational biology, fluid dynamics, and molecular simulations, the firm enables clients to move from molecular development through to virtual clinical trials, serving as a precursor and complement to physical experiments. Their approach focuses on creating transparent and reproducible models that help de-risk workflows from the discovery stage to first-in-human studies.

This technology is intended to improve safety and efficacy while reducing the cost, time, and reliance on animal experimentation inherent in traditional pre-clinical R&D. By providing objective, regulatory-grade evidence, MVT in Silico helps developers address complex biological and regulatory questions, effectively streamlining animal and bench experiments. The company, based in London, Ontario, actively collaborates with pharmaceutical sponsors, academic institutions, and biotech innovators to integrate these advanced simulation workflows into therapeutic development programs, ultimately aiming to reduce the burden of Phase I clinical trials.