Orion Integrated Biosciences

Founded in 2005 and headquartered in Manhattan, Kansas, Orion Integrated Biosciences is a biodefense enterprise that specializes in addressing complex health, trade, and security challenges. The company leverages a multidisciplinary approach that combines bioinformatics, microbiology, and artificial intelligence to monitor, track, and characterize both known and unknown biothreats. Their core technologies include the RIGEL biodefense analytical system, which integrates disparate data sources, and a proprietary computational approach known as Motif Fingerprinting used to analyze genomic information for vaccine and antimicrobial development.

The company focuses on providing critical solutions for public health and national security organizations, including government agencies such as the DoD, NIH, USDA, and DHS. By developing rationally designed vaccines, antimicrobials, and advanced surveillance tools, Orion Integrated Biosciences aims to mitigate the impact of emerging pathogens and drug-resistant microbes. The company maintains an active R&D pipeline supported by strategic alliances with national laboratories, universities, and international research consortiums, ensuring access to high-level biosecurity facilities and essential pathogen data to drive their mission of protecting global health and environmental safety.