unephra

Unephra is a health technology company that has developed a non-wearable, at-home health monitoring ecosystem designed to manage cardiovascular diseases like heart failure and hypertension. The system utilizes proprietary passive urine-monitoring technology, which incorporates an adaptive micro-sensor array to measure biomarkers such as sodium and potassium. By integrating these measurements with advanced machine learning and statistical analysis based on cardio-renal physiological models, the platform translates daily bathroom visits into continuous, real-time clinical insights. This non-invasive and non-intrusive approach differs from traditional wearable devices by offering a seamless user experience that does not require constant patient interaction or equipment management.

This technology aims to shift healthcare from reactive, one-size-fits-all treatments to proactive, personalized care that can be delivered outside of hospital settings. By sharing physiological data directly with care teams, the platform enables providers to make timely, data-driven interventions that are tailored to the patient's unique needs, potentially improving health outcomes and reducing the costs associated with hospitalizations. The company, which is based in San Jose, California, and was founded in 2023, is currently focused on clinical pilots and has begun gaining recognition in the industry, including winning pitch competitions at events such as JPM HealthTech Week. It counts institutions like Stanford's Snyder Lab and Permanente Medicine among its partners.