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AN
Alberto Nobili
Scientific Director
Harvard Medical School & Boston Children's Hospital
Publications
20
Funding
1
Patents
0
Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications
Biotechnology advances 33 (5), 566-604, 2015
Engineering the Active Site of the Amine Transaminase from Vibrio fluvialis for the Asymmetric Synthesis of Aryl–Alkyl Amines and Amino Alcohols
ChemCatChem 7 (5), 757-760, 2015
Use of ‘small but smart’ libraries to enhance the enantioselectivity of an esterase from Bacillus stearothermophilus towards tetrahydrofuran‐3‐yl acetate
The FEBS Journal 280 (13), 3084-3093, 2013
Two subtle amino acid changes in a transaminase substantially enhance or invert enantiopreference in cascade syntheses
ChemBioChem 16 (7), 1041-1045, 2015
Simultaneous use of in silico design and a correlated mutation network as a tool to efficiently guide enzyme engineering
ChemBioChem 16 (5), 805-810, 2015
Creation of (R)-Amine Transaminase Activity within an α-Amino Acid Transaminase Scaffold
ACS Chemical Biology 15 (2), 416-424, 2020
Improved thermostability of a Bacillus subtilis esterase by domain exchange
Applied microbiology and biotechnology 98, 1719-1726, 2014
Light‐Controllable Binary Switch Activation of CAR T Cells
ChemMedChem 17 (12), e202100722, 2022
NewProt–a protein engineering portal
Protein Engineering, Design and Selection 30 (6), 441-447, 2017
CorNet: Assigning function to networks of co-evolving residues by automated literature mining
PLoS One 12 (5), e0176427, 2017
Bioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases
Applied microbiology and biotechnology 101, 1499-1507, 2017
Compositions and methods for targeted immunotherapy
US Patent App. 15/734,116, 2021
Targeting of multiple antigens with multiplex car t cells in solid and liquid malignancies
US Patent App. 17/254,472, 2021
Immunotherapy compositions and methods
US Patent 11,225,520, 2022
Clutch Control: Changing the Speed and Direction of CAR-T Cell Therapy
Journal of cancer immunology 4 (2), 52, 2022
ENGINEERED CYTOKINE RECEPTORS FOR TUNABLE ADOPTIVE CELL THERAPY
US Patent App. 18/699,108, 2024
Compositions and methods for targeted immunotherapy
US Patent App. 18/585,659, 2024
Compositions and methods for targeted tumor immunotherapy
US Patent App. 18/428,872, 2024
Front Cover: Light‐Controllable Binary Switch Activation of CAR T Cells (ChemMedChem 12/2022)
ChemMedChem 17 (12), e202200309, 2022
Compositions and methods for targeted tumor immunotherapy
US Patent App. 16/606,619, 2020
AN
Alberto Nobili
Scientific Director
Harvard Medical School & Boston Children's Hospital
Work experience
Harvard Medical School & Boston Children's Hospital
Scientific Director
Dana-Farber Cancer Institute - Harvard Medical School
Scientific Director
Top industry applications
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Open to opportunities in
Biotechnology
Cardiovascular
Cell Biology
Cell Therapy
Chemical Engineering
Drug Delivery
Last updated Feb 2025
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