Chemical Biology research focused on the polymodification of antibodies to generate antibody drug conjugates but also with a wider interest in protein polymodification. Wider interest in small molecule targeted therapeutics.
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Research mainly focused on the production of homogeneously polymodified antibody drug conjugates for use in oncology. Utilisation of a branched chemical linkers/bioorthogonal chemistry to achieve these aims and understand potential drug synergies.
In addition to this area of research the lab is also interested in the development of novel small molecule/targeted anti-fungal and anti-bacterial agents.
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