I have developed patented and patent pending topicals-with-light technologies augmenting skin penetration of bioactive substances for cosmetic and medical applications. My latest development uses plant-based lipophilic high refractive index topical systems to significantly augment light transmission through the stratum corneum for cosmetic and musculoskeletal light therapies. This method/ topical system eliminates dark skin tone light therapy light power restrictions, skin surface light trapping/ light confinement and skin surface heating from applied light energy.