Francesco antonio Aprile's profile

Francesco antonio Aprile

Principal Investigator

Imperial College London

I'm working on

3 years ago

Integrative antibody discovery

About

Our team develops biomolecules as research tools for understanding disease mechanisms and clinical applications. We use innovative high-throughput discovery methods to generate antibodies and peptides to study how the complex environment of the body modifies and modulates proteins.

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Imperial College London

Conformation-specific nanobody targeting alpha-synuclein oligomers for neurodegeneration theragnostics

A nanobody that selectively binds the P1 region (residues 36–42) of alpha-synuclein, enabling specific targeting of toxic oligomeric self-assemblies implicated in Parkinson's and Alzheimer's disease. The nanobody inhibit...

TechnologyConceptualUniversity

Francesco antonio Aprile

Principal Investigator

Imperial College London

Work experience

University of Cambridge

Postdoctoral Scientist

2013 - 2019

Imperial College London

Principal Investigator

2009 - 2019

Universita degli Studi di Milano-Bicocca