Guoku Hu's profile

Guoku Hu

Principal Investigator

University of Nebraska Medical Center

I'm working on

7 months ago

Neuroimmunology, Extracellular Vesicles, RNA Therapeutics, CNS Delivery

About

Focus on glia-derived extracellular vesicles and noncoding RNA regulation to modulate neuroimmune signaling. Develops intranasal EV delivery to target microglial function and ciliary pathways implicated in neuroinflammation and opioid tolerance.

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University of Nebraska Medical Center

Exosome-based siRNA delivery targeting lincRNA-Cox2 for multiple sclerosis treatment

A novel therapeutic approach using exosomes to deliver siRNA targeting lincRNA-Cox2, a key regulator of neuroinflammation, to treat multiple sclerosis. This delivery platform aims to reduce disease severity, decrease neu...

TechnologyConceptualUniversity

Guoku Hu

Principal Investigator

University of Nebraska Medical Center

Work experience

University of Nebraska Medical Center

Principal Investigator

Top industry applications

Neurology & neurological diseasePharmaceuticals and drug delivery

Open to opportunities in

BiotechnologyCell BiologyCell TherapyGene TherapyGenomics

Last updated Mar 2026