Joseph Jez's profile

Joseph Jez

Principal Investigator

Washington University in St. Louis

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9 months ago

Plant hormone signaling, enzyme mechanisms, plant–microbe interfaces

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Integrates structural biology, biochemistry, and physiology to resolve prereceptor hormone modulation and metabolic crosstalk, connect enzyme mechanism to whole-plant responses, and inform strategies for herbicide tolerance, disease outcomes, and heat‑stress resilience in major crops.

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Washington University in St. Louis

Engineered GH3 enzymes for targeted inactivation of 2,4-D herbicide through amino acid conjugation

A structure-guided enzyme engineering platform that modifies plant GH3 acyl acid amido synthetases to conjugate and inactivate the widely used herbicide 2,4-D. Leveraging characterized activity of AtGH3.15 with the relat...

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Joseph Jez

Principal Investigator

Washington University in St. Louis

Work experience

Washington University in St. Louis

Principal Investigator

2002 - Present

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