Matthias Trost's profile

Matthias Trost

Principal Investigator

Newcastle University

I'm working on

7 months ago

Proteomics, Mass Spectrometry, High‑Throughput Drug Discovery

About

I develop high‑throughput, label‑free mass‑spectrometry workflows for biochemical and cellular assays. We enable multiplexed screening, enzyme‑pathway profiling, and proteome‑level target engagement to accelerate small‑molecule discovery across human disease.

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Newcastle University

High-throughput MALDI TOF mass spectrometry platform for 5α-reductase inhibitor screening

A label-free, high-throughput MALDI TOF mass spectrometry screening platform adapted for 5α-reductase (5α-R1 and 5α-R2) inhibitor discovery. The assay directly measures testosterone-to-dihydrotestosterone conversion via ...

Facilities & testingUniversity

Matthias Trost

Principal Investigator

Newcastle University

Work experience

Newcastle University

Principal Investigator

Top industry applications

Pharmaceuticals and drug delivery

Open to opportunities in

Analytical ChemistryBiochemistryCell BiologyInfectious DiseasesProteomics

Last updated Feb 2026