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Shiva Shahrara
Principal Investigator
University of Illinois Chicago
I'm working on
16 days ago
Leveraging extensive access to RA blood & synovial tissue, our recent papers (PMIDs 42697828, 41781698, 37150238, 38105293) identify novel therapeutic targets & biomarkers. We highlight how immunometabolism drives pathogenic myeloid crosstalk with FLS & endothelial cells.
About
Our translational rheumatology program is powered by exceptional access to RA patient blood and primary synovial tissue. We investigate how immunometabolism drives pathogenic crosstalk between myeloid cells, fibroblast-like synoviocytes (FLS), and endothelial cells in the inflamed joint. By deconstructing these multicellular networks, we identify novel therapeutic targets and predictive biomarkers for RA. Backed by high-impact publications and a proven track record of successful alliances with top-tier pharmaceutical leaders, we are actively seeking new industry partners. We offer robust, human-tissue-based platforms for preclinical therapeutic testing and biomarker discovery to accelerate the development of next-generation RA treatments.
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Shiva Shahrara
Principal Investigator
University of Illinois Chicago
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Principal Investigator
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ImmunologyImmunotherapyMetabolomicsTranslational Science
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Last updated Oct 2026
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