In vitro screening of steroid 5-alpha reductase inhibitors using purified enzyme and LC-MS/MS quantification
BioNotus offers a contract research service for screening 5-alpha reductase inhibitors using purified human enzyme combined with a validated LC-MS/MS dihydrotestosterone quantification assay. The platform delivers reprod...
In silico preselection of fungicide potentiator candidates
An innovative approach leveraging in silico prescreening to identify fungicide potentiators that target resistance mechanisms, enhancing fungicide efficacy. This method aims to increase efficiency and synergy by focusing...
Biorelevant in vitro platform for enhanced micronutrient bioavailability
BioNotus introduces a biorelevant in vitro platform using Physiology-Based BioNeutraceutics Modelling to enhance micronutrient bioavailability. This cost-effective solution integrates in vitro and in silico methods to op...
Stress mitigation through botanicals using LC-MS/MS and qpcr
BioNotus is developing a robust in vitro screening assay to evaluate stress-mitigating botanicals. Using advanced techniques like LC-MS/MS and qPCR, the technology aims to identify stress-inducing and mitigating compound...
Quantitative mycotoxin detection in grain extracts using UPLC-MS/MS
Advanced UPLC-MS/MS technology offers superior sensitivity and specificity for detecting mycotoxins in food matrices compared to traditional HPLC with UV detection, enhancing method development and sample analysis effici...
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