In-air microfluidics microencapsulation

In-Air Microfluidics™ — High-Throughput, Biocompatible Microencapsulation with Microfluidic Precision

IamFluidics’ patented In-Air Microfluidics™ technology combines industrial throughput, rapid processing, tight size distributions, and biocompatibility in a single microencapsulation platform. The technology produces highly monodisperse microparticles and microcapsules with diameters typically ranging from ~30 µm up to several millimeters, while maintaining coefficients of variation commonly below 5–10%, even at high production rates (up to 1000x faster than conventional chip-based microfluidics).

Droplets are generated in free space rather than inside microfluidic chips. This chip-free architecture eliminates clogging, supports low-shear encapsulation, and enables reliable processing of a wide range of viscosities and formulations. Sensitive payloads—including live cells, biologics, probiotics, enzymes, and functional actives—can be encapsulated without toxic solvents, surfactants, or microplastics, preserving viability and functionality.

Throughput is increased via parallelization, allowing smooth scale-up from laboratory development to continuous, industrially relevant production without loss of particle uniformity or batch-to-batch consistency. The platform delivers precise control over particle size, morphology, and composition, supporting reproducible release profiles and consistent product performance.

In-Air Microfluidics™ is used across pharmaceuticals, cell therapy, food, cosmetics, and advanced materials, offering a scalable and sustainable alternative to emulsification, spray drying, vibrating nozzles, and chip-based microfluidics—when speed, quality, and biological integrity must coexist.