Wearable sweat sensor for real-time hormone detection

Technology
In development
University

Innovative wearable sensor using microbial nanocellulose and screen-printed carbon electrodes for non-invasive, real-time monitoring of estrogen and progesterone. Offers high sensitivity and user comfort, with potential for wireless data transmission to smartphones.

Overview

This wearable sweat sensor is designed for the real-time detection of hormones such as estrogen and progesterone. Utilizing microbial nanocellulose (MNC) as a substrate, it offers a non-invasive and user-friendly solution for hormone monitoring. The sensor integrates screen-printed carbon electrodes (SPCEs) that are functionalized via molecular imprinting to ensure selective and sensitive detection. The biocompatible and skin-conformable nature of MNC enhances user comfort, making it suitable for daily wear.

Technical specifications
  • Substrate: Utilizes microbial nanocellulose for its breathability, skin adhesion, and biocompatibility.
  • Detection Mechanism: Employs screen-printed carbon electrodes functionalized with molecularly imprinted polymers for selective hormone detection.
  • Data Transmission: Plans to incorporate a miniaturized wireless communication module for data transmission to a smartphone app.
  • Power Source: Investigating the integration of triboelectric nanogenerators to enable self-powering through body movements.
  • Performance Metrics: Electrochemical characterization will determine sensitivity, selectivity, and detection limits, with a focus on interference-free operation in sweat.
Technology readiness level

Currently at TRL 4, this technology is in the prototyping phase with ongoing efforts to optimize electrode functionalization and sensor performance. Future steps include extensive testing under both simulated and real conditions, user trials for comfort and usability, and potential integration of self-powering systems.


About Universidade Estadual de Campinas

Universidade Estadual de Campinas (Unicamp) is a comprehensive public research university in Campinas, São Paulo, recognized for high research intensity and strong graduate education. Industry engages through an on‑campus science and technology park with co‑located corporate R&D suites and shared core facilities. Clinical translation is enabled by an integrated teaching hospital and specialized centers, while proximity to the Campinas–São Paulo innovation corridor makes onsite collaboration and talent access straightforward. Research is supported by state and federal agencies such as FAPESP, CNPq, CAPES, and FINEP, alongside industry contracts. A dedicated technology transfer office manages IP, licensing, and startup formation, and offers clear pathways for NDAs, sponsored research, and scale‑up.

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