Select amino acids and plant extracts for enhanced skin repair and regeneration

Technology
In development
University

This innovative formulation uses select amino acids and plant extracts to enhance skin barrier function, reducing inflammation and promoting skin regeneration. By improving keratinocyte proliferation, the solution offers a promising approach to skin repair and hydration.

Overview

This innovative solution leverages the synergistic effects of select amino acids and plant extracts to enhance skin barrier function and promote effective skin repair and regeneration. By reducing the translocation of allergens, pollutants, and bacteria, this formulation decreases inflammation and supports the natural regenerative processes of the skin. The active ingredients target barrier function and epithelial stem cell proliferation, offering a comprehensive approach to improving skin health and hydration.

Technical specifications

Key features:

  • Combines amino acids and plant extracts to boost skin barrier function
  • Reduces inflammation by decreasing proinflammatory cytokines
  • Enhances keratinocyte stem cell proliferation for effective skin regeneration
  • Utilizes botanical compounds, amino acids, peptides, and plant-based sugars
  • Evaluated using 2D and 3D primary human keratinocyte wound models
  • Promotes skin hydration and antimicrobial properties
  • Increases EGF levels and activates epithelial transporters and channels
Technology readiness level

This technology is at Technology Readiness Level 5, with ongoing validation using human epithelial keratinocyte models to demonstrate its efficacy in skin repair and regeneration.


About University of Florida

The University of Florida is a comprehensive public research university with a broad academic and research portfolio and a statewide presence. Industry collaborates through co-located labs and shared core facilities and through an integrated academic health system that accelerates clinical translation. A statewide extension network and multiple research and education sites connect companies with field-scale testing and rapid deployment, while incubators and an adjacent innovation district provide pathways from lab to market. Research is supported by competitive funding from major federal agencies such as NIH, NSF, USDA, and DOE. A dedicated technology transfer office supports IP, licensing, and startup formation.

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