Advanced 3D printing bioinks for realistic pelvic tissue models
This research focuses on developing 3D printable bioinks that accurately mimic the mechanical behavior of pelvic tissue. By characterizing the viscoelastic properties and microstructure of specific tissues, the project aims to create sophisticated models for training and potential implant usage.
Overview
This innovative research project aims to develop 3D printable bioinks capable of replicating the complex mechanical properties of pelvic tissue. By focusing on the viscoelastic properties and microstructural features of tissues surrounding the human hip joint, the project seeks to create biomaterials with targeted microfiber architecture. These can be used to produce realistic models that mimic the compliance of native human tissue, offering significant advancements in medical training and the potential for biocompatible implantable grafts.
Technical specifications
- Characterization of soft tissue: Detailed analysis of the viscoelastic behavior and microstructural features, such as crimp angle and fiber type, of ligaments, tendons, and muscles near the hip joint using advanced mechanical testing.
- Additive manufacturing platform: Utilizes an innovative multiscale, multimaterial process to optimize fiber deposition in 3D printed models, enhancing their mechanical fidelity.
- Computational modeling: Development of models to mathematically represent tissue behavior under cyclic loading, aiding in the accurate reproduction of tissue responses.
- Microscopy techniques: Employ advanced microscopy to visualize tissue microstructure, facilitating replication through additive manufacturing.
Technology readiness level
This technology is currently at TRL 4, indicating that it has been validated in a lab environment. Future work will involve further mechanical characterization and model refinement to enhance realism and functionality for medical applications.
About University of New Mexico
The University of New Mexico is New Mexico’s flagship public research university centered in Albuquerque, combining broad academic strengths with a strong applied research culture. An integrated academic health center enables clinical collaboration and translational studies at scale. A research and technology park and a downtown innovation district provide incubator space, shared labs, and options for corporate co-location alongside faculty and student talent. Proximity to major federal laboratories and Air Force research facilities supports partnerships, user access to specialized instrumentation, and sponsored projects. Research is sustained by competitive funding from NIH, NSF, DOE, and DoD, with a dedicated technology transfer office facilitating IP, licensing, and startup formation.
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