Scalable custom polypills for VMS dosing using 3D drug printing
InfraTrac offers a novel approach to personalized medicine through 3D printed polypills, combining geometric control for precise dosing with NIR spectroscopy for quality assurance. Seeking VMS partners to enhance product differentiation and customer satisfaction.
Overview
InfraTrac is revolutionizing the field of personalized medicine with its innovative approach to 3D drug printing. By designing scalable custom polypills, InfraTrac enables personalized dosing through precise geometric control. This allows for advanced controlled release mechanisms and enhanced patient compliance. The key innovation lies in the use of near-infrared (NIR) spectroscopy combined with chemometric modeling to verify ingredient accuracy and print success in real-time, ensuring high quality and safety standards.
Technical specifications
Key features:
- 3D Printing Techniques: Utilizes FDM from drug-containing filaments, DPE from pharmaceutical powders, and SSE from single-use syringes, alongside capsule and blister-filling modes.
- Precision Dose Control: Introduces a novel core-shell-cap design (patent pending) for hour-by-hour tuning of drug release, enhancing control and effectiveness.
- Quality Assurance: Incorporates NIR spectroscopy for in-line verification of doses and ingredients, supported by chemometric modeling.
- Polypill Design: Enables combination of multiple medications in a single pill, customized for individual patient needs.
Technology readiness level
Currently at TRL 4, InfraTrac has demonstrated lab-scale validation of its 3D drug printing protocols. The next steps involve collaboration with VMS manufacturers to optimize formulations and test parameters for commercial scalability and regulatory compliance.
About InfraTrac, Inc
InfraTrac, Inc. is a woman-owned technology company that specializes in light-based innovation for anti-counterfeiting, quality assurance, and controlled release applications. Founded in 2006, the company leverages near-infrared (NIR) spectroscopy and light-activated chemical signatures to provide authentication solutions. Its technology is designed to verify the integrity of products by comparing them against chemometric reference models, which is particularly useful for additive manufacturing. By analyzing how materials respond to light, InfraTrac provides a non-destructive, rapid, and precise method to confirm that products meet specified standards without requiring extensive operator training.
This technology is utilized across industries including pharmaceuticals and aerospace, where ensuring material authenticity and quality is critical. In the pharmaceutical sector, for instance, the company provides tools for hospital pharmacies to verify that 3D-printed doses contain the correct concentrations of active ingredients, helping to prevent the administration of non-conforming medication. InfraTrac has received competitive funding and contracts from organizations such as the National Institutes of Health (NIH), the National Institute of Standards and Technology (NIST), and Lockheed Martin to advance its spectroscopic quality and authentication capabilities. The company continues to innovate in the development of 3D-printed nano-scale containers aimed at improving the controlled release of payloads for medical and industrial applications.
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