Rapid isothermal SNP detection with SNAAT technology

Overview

SNAAT (Streamlined Nucleic Acid Amplification Technology) is a proprietary, LAMP-based method designed for the rapid and accurate detection of single nucleotide polymorphisms (SNPs) from non-invasive samples such as saliva and cheek swabs. This technology is particularly suited for point-of-care testing (POCT) as well as centralized laboratory settings, providing high sensitivity and specificity (≥95%) essential for consumer health applications and personalized nutrition services. SNAAT's fast turnaround time of under 30 minutes, coupled with its low cost per sample (≤$10), ensures a strong return on investment for high-volume applications.

Technical specifications

• Proprietary LAMP-based method: Utilizes isothermal amplification for rapid SNP detection.
• Non-invasive sampling: Compatible with cheek swabs and saliva, facilitating user-friendly sample collection.
• High sensitivity and specificity: Achieves ≥95% on both metrics, validated against therapy-related SNPs.
• Cost-effective and scalable: Supports low-cost reaction cards and mobile device integration for POCT, with automation potential for centralized labs.
• Fast results: Provides results in under 30 minutes, crucial for timely decision-making in consumer health.

Technology readiness level

Currently at TRL 5, SNAAT has undergone validation for analytical accuracy and compatibility with therapy-related SNPs. The technology is in the process of optimization and scale-up, with real-world field trials and regulatory preparations underway.