Sprayable biocompatible adhesive for wound closure

Technology
In development
Company

Zentraxa's innovative adhesive offers a sprayable, rapid-cure solution for wound closure, compatible with bioactive additives. This biocompatible formula bonds effectively to wet surfaces, providing a barrier against pathogens and debris.

Overview

Zentraxa introduces a novel biocompatible adhesive designed for sprayable application in wound closure treatments. This advanced adhesive is bio-based, functioning efficiently in wet environments, and offers a safer alternative to traditional organophosphate-based formulations. The technology is adaptable for a spray-on application, potentially revolutionizing how wounds are treated by providing an effective barrier against debris and pathogens while allowing for the inclusion of insecticide and antiseptic additives.

Technical specifications
  • Biocompatible chemistry: Ensures safety and compatibility with biological tissues.
  • Rapid curing: Achieves bond strengths exceeding 1MPa in less than 3 minutes.
  • Versatile bonding: Effective on various surfaces including keratin and skin, even when wet or dirty.
  • Compatibility: Likely compatible with additives like doramectin, moxidectin, and spinosad, though fipronil may not be suitable.
  • Spray application: Designed for use with equipment like the Walther PILOT 2K Bonding Gun, applicable directly on wounds or through sterile dressings.
  • Debonding strategies: Allows for easy removal without damaging underlying tissue.
Technology readiness level

Currently at TRL 5, the adhesive has undergone significant development and testing phases. Future validation steps include integrating bioactives into the formula, performance testing for wound closure and barrier effectiveness, and developing a proof of concept for the sprayable application. These steps are expected to further advance the technology towards commercialization.


About Zentraxa Ltd

Zentraxa Limited is an engineering biology company that develops nature-inspired, highly-functional bio-adhesives. At the core of the company is its proprietary Zentide platform, which leverages synthetic biology to create scalable peptides designed for specific adhesive functions. These materials are engineered to be industrially robust, allowing for simple integration into existing manufacturing processes. By taking inspiration from marine mussels and other natural systems, Zentraxa creates products that perform effectively in challenging conditions, including wet, high-friction, and submerged environments. The company focuses on developing sustainable, high-performance alternatives to conventional chemical adhesives, with specific applications in sectors such as personal care, advanced wound care, medical wearables, transport, and structural industrial settings. Zentraxa collaborates with industry partners to integrate these ingredients into bespoke solutions, aiming to address problems related to durability, pain-free medical dressing removal, and material performance in extreme conditions. The technology also offers capabilities for de-bondable adhesives in optics and security, as well as functional ingredients for strengthening and protecting hair in personal care applications.

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