Totipro® PE0301 is a clinically validated postbiotic designed to modulate the oral microbiome and support gum health. Utilizing Glac Biotech's HeaLAC® technology, it targets disease-associated bacteria while enhancing mucosal immunity, suitable for various oral care products.
Totipro® PE0301 is an innovative postbiotic ingredient designed to enhance oral health by modulating the oral microbiome. Developed using Glac Biotech's proprietary HeaLAC® technology, this solution specifically targets harmful bacteria associated with gum diseases such as gingivitis. By selectively suppressing pathogens like Streptococcus mutans and Porphyromonas gingivalis, PE0301 helps maintain a balanced oral microbiome and boosts mucosal immunity through increased salivary IgA. The ingredient has been clinically validated in a randomized human study, demonstrating significant improvements in oral microbiota and health parameters. It is versatile for inclusion in products like toothpaste, mouthwash, lozenges, chewing gum, and oral sprays.
Totipro® PE0301 is at Technology Readiness Level 9, indicating that it is commercially available and supported by extensive clinical, safety, and stability data. Consumer products incorporating this ingredient are already on the market, showcasing its commercial feasibility and scalability.
Glac Biotech is a biotechnology company specializing in the development and supply of probiotic and postbiotic ingredients. The company utilizes proprietary fermentation platforms, including its patented HeaLAC heat-killing process and high-density fermentation technology, to produce functional ingredients such as its Totipro postbiotic fermented powders and PRONULIFE probiotic series. These products are designed to offer increased stability, longer shelf life at room temperature, and versatile application options for various health-focused products. By leveraging scientific screening and rigorous stability testing, the company provides concentrated probiotic metabolites that support digestive and immune health, positioning itself as an ingredient supplier and partner for ODM, OEM, and CDMO services. Their solutions enable manufacturers to integrate functional ingredients into diverse formulations without the traditional storage limitations associated with live probiotics.