Molecular detection system (MDS)
The Neogen MDS is a LAMP-based pathogen testing platform combining isothermal DNA amplification with bioluminescence detection, selected by USDA FSIS as its primary method for Salmonella and Listeria detection. Used in 40+ countries.
Overview
The MDS platform uses loop-mediated isothermal amplification (LAMP) to detect pathogen DNA without thermal cycling. After sample enrichment, the assay amplifies target DNA at a constant temperature while a bioluminescent reporter generates a real-time light signal. This delivers results faster than traditional PCR with equivalent or superior sensitivity, in a simpler workflow requiring less training. USDA FSIS selected MDS as its primary detection method for Salmonella, Listeria monocytogenes, and Listeria spp.
Technical specifications
- Technology: loop-mediated isothermal amplification (LAMP) with bioluminescent detection
- Pathogen assays: Salmonella, Listeria monocytogenes, Listeria spp., E. coli O157:H7, Campylobacter, STEC gene screen (stx and eae), Cronobacter, Salmonella Enteritidis/Typhimurium
- Regulatory: selected by USDA FSIS as primary detection method for Salmonella and Listeria
- Global use: food processors, universities, government labs, and contract testing laboratories in 40+ countries
- Throughput: 96-test kit format
- Advantages over PCR: no thermal cycling, simpler workflow, reduced operator training
Technology readiness level
TRL 9 — commercially established with USDA FSIS primary method designation and global adoption.
About Neogen
Neogen Corporation is a global leader in food and animal safety, providing data-driven solutions for food processing, animal protein, agriculture, and pet health industries. The company develops and markets a wide-ranging portfolio that includes diagnostic testing for foodborne pathogens, allergens, and mycotoxins, as well as veterinary instruments, pharmaceuticals, and disinfectants. By leveraging science and technology, Neogen offers tools such as its Petrifilm monitoring systems and advanced analytics software to help the industry detect contamination, ensure regulatory compliance, and support operational efficiency throughout the food chain.
These solutions are critical for food safety leaders, livestock producers, and pet care professionals who operate in complex regulatory and operational environments. Neogen’s offerings help stakeholders manage risk, improve animal health, and safeguard the food supply. By integrating testing technologies and data-backed insights, the company enables customers to prevent foodborne illness and optimize productivity. Through its focus on innovation and commercial excellence, Neogen continues to scale its global reach to meet the evolving safety and quality demands of the modern food and agriculture sectors.
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