Revysol® (mefentrifluconazole) fungicide

Overview

Repeated triazole use has selected for resistant Septoria tritici and Ramularia collo-cygni populations that reduce older molecule efficacy. Revysol's novel binding geometry at the CYP51 target site — enabled by its isopropanol moiety — maintains binding affinity against mutant enzymes. Registered for cereals, oilseeds, fruits, and vegetables globally.

Technical specifications

• Active ingredient: mefentrifluconazole (Revysol)
• Chemical class: isopropanol-azole (triazole subclass)
• Mode of action: sterol 14-alpha demethylase (CYP51) inhibition (FRAC Group 3) with novel binding geometry
• Resistance management: maintains activity against triazole-adapted Septoria tritici and Ramularia collo-cygni
• Target diseases: Septoria leaf blotch, Ramularia leaf spot, rusts, powdery mildew
• Crops: wheat, barley, oilseed rape, fruits, vegetables
• Formulated products: Revystar (with fluxapyroxad), Revytrex, and other co-formulations

Technology readiness level

TRL 9 — commercially registered and in field use across major cereal-producing regions.