Additive manufacturing systems for personalized nutraceuticals
Advanced robotic systems blend and encapsulate personalized nutraceuticals for targeted health benefits, utilizing a digital recipe and automated processes for high efficiency and precision.
Overview
OneFul Health Inc. introduces a cutting-edge additive manufacturing system designed to personalize nutraceuticals. This innovative robotic technology enables the precise blending of micro and macro nutrients with nutraceutical ingredients into customized formulations. Utilizing a digital recipe, these ingredients are homogenized with a flavored thixotropic suspension carrier, creating ready-to-consume pouches with a 24-month shelf life. This system is ideal for delivering therapeutic levels of vitamins, minerals, proteins, and other specialized compounds, ensuring targeted health benefits, such as controlled release of pre- and post-biotics in the colon.
Technical specifications
The system employs advanced robotic automation to accurately dose ingredients into small batches (1-3 liters) and capsules. A "polypill" capsule filler component can additively dose powdered ingredients into capsules, producing up to 1800 capsules per hour. This technology is supported by a formulation library of stability-tested intermediate forms and utilizes specialized micro-encapsulation techniques to enhance delivery to specific intestinal regions. The process adheres to cGMP standards and has been demonstrated in commercial settings, validating its effectiveness for large-scale production.
Technology readiness level
The technology is at TRL 8, having been tested in operational environments and validated in commercial cGMP facilities. Future developments include co-developing pilot products for specific health conditions, such as diabetes and obesity therapy, utilizing existing processes to ensure rapid deployment and market readiness.
About OneFul Health Inc.
OneFul Health is an e-pharmacy for personalized combination therapies. It uses custom formulation software and patented pharmacy technology to deliver multi-drug prescriptions combined as a single pill or gel packet, with physician-approved formulations. The company positions its platform around multi-drug combination products (e.g., 3–7 medicines for daily chronic therapy) intended to reduce pill burden and improve adherence; it describes prescriptions being checked and released by its PharmD team using patented automation, followed by direct delivery to the patient typically within about 24 hours after receipt. OneFul also describes its technology platform as supporting individualized formulation informed by a patient’s genomic information paired with pharmaceutical pharmacogenomics (PGx) data.
This matters for patients managing chronic conditions that often require multiple pills and experience “pill fatigue,” missed doses, and complex day-to-day organization. OneFul presents its approach as simplifying medication routines by consolidating prescribed medicines into a single easy-to-take form while aiming to reduce adverse effects and improve effectiveness via individualized drug selection/dosing. The company’s SEC filings identify OneFul Health Inc. as the issuer behind the OneFul effort and include the company name, address, and that it operates the OneFul business at the referenced website domain.
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