Anti-biofilm bacterial resistance fighting gentle mouth rub
Revolutionary dental rub that inhibits biofilm formation and fights bacterial resistance using a silver chitosan lactate gel. Effective against gram-positive and gram-negative bacteria, yeasts, and feline corona viruses, while ensuring safety and non-toxicity.
Overview
The anti-biofilm bacterial resistance fighting gentle mouth rub is an innovative dental solution designed to inhibit bacterial resistance and adaptation. This daily or bi-daily application forms a micron-thin protective film over teeth and gums, providing long-lasting defense against a broad spectrum of pathogens, including gram-positive and gram-negative bacteria, yeasts, and feline corona viruses. The medical-grade gel, containing a silver chitosan lactate called Glucosil, offers a safe and effective alternative to traditional oral care products.
Technical specifications
- Active Ingredient: Silver chitosan lactate (Glucosil) bound with natural Van der Waals forces to prevent silver leaching and toxicity.
- Effectiveness: Demonstrated efficacy in inhibiting and eliminating biofilms, with proven safety in animal studies and OTC skin product applications.
- Safety Profile: Passed toxicity tests, does not accumulate in organs, and is safely excreted via the kidneys if ingested.
- Application: Easy-to-apply dental rub, not a toothpaste, with potential for flavored gel formulations.
Technology readiness level
The technology is currently at TRL 4, having undergone successful lab studies demonstrating its efficacy and safety. Future validation plans include further formulation testing, efficacy evaluation, stability assessments, and flavor testing to advance development and market readiness.
About Chitozan Health LLC
Chitozan Health LLC is a biotechnology research firm that develops antimicrobial solutions utilizing patented silver-chitosan technology [1][3][5]. Their core innovation, marketed as Silver Shell or Glucosil, incorporates chitosan and silver particles to create durable, effective antimicrobial barriers for various applications [1][5][8]. By leveraging the biostatic properties of chitosan, the company produces textile finishes and topical gels that are designed to combat pathogens, including bacteria, fungi, and viruses, while minimizing the use of silver and maintaining safety standards [1][5][8]. This research is supported by NIH NIAID funding and focuses on managing infections, such as those related to Pseudomonas aeruginosa in cystic fibrosis, as well as providing broad-spectrum protection in healthcare and consumer settings [1][5][7].
These products serve a range of stakeholders, from industrial partners in textile manufacturing and sustainable packaging to healthcare providers and individual consumers in need of advanced wound and burn care [1][4][7][8]. The company's technology addresses critical challenges such as antimicrobial resistance, infection control, and the environmental impact of synthetic materials [1][4][8]. Through rigorous independent laboratory testing, their treatments have demonstrated significant efficacy in reducing pathogen populations and sustaining performance even after multiple commercial wash cycles [1][5]. With a focus on sustainable, naturally derived materials, Chitozan Health aims to provide safer, more effective alternatives for infection mitigation across multiple sectors [1][7].
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