Automating mass customization of solid dosage forms with craft health 3D platform
Craft Health's innovative 3D printing technology enables automated mass customization of pharmaceutical, nutraceutical, and food products. Utilizing a heat and UV-free method, it ensures precise, contamination-free production of various dosage forms with customizable release profiles.
Overview
Craft Health Private Limited presents a pioneering solution for the automated mass customization of solid dosage forms using its advanced 3D printing platform. This technology allows for the precise customization of pharmaceuticals, nutraceuticals, and food products, offering versatility in dosage forms such as tablets, capsules, and gummies. The platform supports multiple active ingredients and release profiles, enhancing product personalization without the need for heat or UV exposure.
Technical specifications
The platform comprises three key components:
- CraftMake 3D Printer: Employs a semi-solid extrusion method that is both heat and UV-free, ensuring minimal contamination and maintaining ingredient integrity. The printer supports up to 10 compartments for varied release profiles or multiple active ingredients.
- CraftControl Software: Enhances the accuracy and precision of printed dosage forms with audit trail functionality, ensuring consistent quality.
- CraftBlend Formulation: A standardized pre-mix of FDA GRAS-listed excipients, designed for immediate, sustained, or delayed release profiles. The platform's open-source nature allows for printing of proprietary formulations within specifications.
Technology readiness level
The Craft Health 3D printing platform is at Technology Readiness Level 6, indicating a technology that has been validated in relevant environments. The future validation plan includes extensive testing and optimization to ensure efficacy, safety, and quality of the printed products, with repeatability of the process to confirm parameter validation.
About Craft Health Private Limited
Craft Health is a deep-tech pharmaceutical and nutraceutical drug delivery company based in Singapore that specializes in 3D-printed personalized medicine. Founded in 2019, the company provides an end-to-end platform that integrates hardware, software, and specialized formulations to automate mass customization of solid dosage forms. Its core technology suite includes CraftMake, a proprietary 3D printer, and CraftBlends, a database of 3D-printable formulations that allow for controlled release without the use of heat or ultraviolet light. This enables the creation of complex tablets where different active ingredients are printed in separate compartments to manage release profiles or prevent ingredient mixing, supporting varied dosage forms such as tablets, beads, and gummies.
The company's platform addresses significant challenges in drug delivery and manufacturing, including the need for rapid prototyping and low-volume, high-mix production. By simplifying the manufacturing process, Craft Health offers solutions for clinical trial testing, personalized medication, and supplement development. The technology is designed to help drug developers improve molecule deliverability, offering an alternative to traditional, less flexible manufacturing methods. The company operates from headquarters in Singapore and serves as a bridge between research, development, and pilot-scale manufacturing for its partners in the life sciences and healthcare sectors.
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