Bacteriocin and enzymatic profile exploration of bacterial strains

Technology
Conceptual
University

Discover novel bacteriocins and enzymatic profiles in bacterial strains using phenotypic tests and bioinformatics. This research aims to optimize bacteriocin production and explore symbiotic applications of rare sugars and fibers.

Overview

This research focuses on the exploration of bacteriocins and enzymatic profiles in bacterial strains through phenotypic tests and bioinformatics. The primary goal is to discover novel bacteriocins that can act against gram-positive and gram-negative bacteria and to optimize their production. Additionally, the study aims to explore enzymatic profiles for symbiotic applications, particularly in the use of rare sugars and fibers.

Technical specifications

Key features:

  • Utilizes phenotypic methods to detect bacteriocin activity.
  • Employs bioinformatics to identify known bacteriocins within bacterial genomes.
  • Optimizes bacterial production if potential bacteriocins are discovered.
  • Tests for proteinase activity and carbon source utilization to identify enzymatic profiles.
  • Explores symbiotic approaches involving rare sugars and fibers.
  • Equipped with traditional and class 2 microbiology lab facilities for comprehensive testing.
Technology readiness level

This research is currently at Technology Readiness Level 3, where active research and early validation are being conducted in a laboratory setting. Full characterization and optimization of potential bacteriocins and enzymes will follow once initial discoveries are made.


About University of Limerick

The University of Limerick is a comprehensive public research university on a riverside campus in Ireland, enrolling approximately 18,000 students. UL pioneered cooperative education in Ireland and maintains deep employer ties through a mature, credit‑bearing work‑placement model. The campus is adjacent to the National Technology Park, giving companies direct access to university expertise and shared facilities. The Nexus Innovation Centre incubates startups on site, and a dedicated technology transfer office streamlines IP, licensing and spin‑out formation. Integration with the UL Hospitals Group connects researchers to a regional clinical network for translation, and research draws competitive support from Science Foundation Ireland and the European Union.

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