Beta-hydroxybutyrate and citrate-enhanced sports drinks for analgesic benefits

Technology
Conceptual
University

This innovative sports drink formulation includes beta-hydroxybutyrate and citrate to provide analgesic benefits and deliver essential ions like calcium and magnesium. It is designed for athletes seeking enhanced recovery and performance through exogenous ketones.

Overview

This solution introduces a novel sports drink formulation that leverages beta-hydroxybutyrate (BHB) and citrate to offer analgesic benefits while supplying essential ions such as calcium and magnesium. The drink is sweetened with stevia, ensuring a palatable taste without added sugars. It aims to support athletes and individuals who exercise regularly by enhancing recovery and performance through the provision of exogenous ketones.

Technical specifications

Key features:

  • Beta-hydroxybutyrate and citrate supplementation: Provides analgesic benefits, potentially reducing post-exercise pain and discomfort.
  • Delivery of essential ions: Supplies calcium and magnesium, which are crucial for muscle function and recovery.
  • Palatable formulation: Sweetened with stevia to ensure a pleasant taste without the use of artificial sweeteners or sugars.

Proposed validation:

  • Testing with 25 participants post-exercise for 2 weeks against a control group consuming water or other sports drinks.
  • Evaluation of safety, feasibility, and tolerability based on participant feedback.
  • Potential biochemical analysis including serum creatine kinase and kidney function tests.
Technology readiness level

The technology is currently at TRL 3, indicating that it is in the experimental proof of concept stage. Further validation is planned to advance its readiness and confirm its efficacy and safety in a broader population.


About University of Southern California

USC is a large, comprehensive private research university in Los Angeles, anchored by two urban campuses and an academic health system. Industry engages through applied research institutes such as the Information Sciences Institute, co-located engineering and clinical facilities, and flexible sponsored research contracting. Proximity to the region’s aerospace, media, and biotech corridors provides access to testbeds, talent, and pilot-scale partners across the greater L.A. innovation economy. Research is supported by competitive federal funding from NIH, NSF, and other major agencies alongside significant industry-sponsored awards. A dedicated technology transfer office supports IP strategy, licensing, corporate partnerships, and venture formation.

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