BIOFILM BARRIER™: Cyclodextran technology for oral biofilm inhibition
BIOFILM BARRIER™ utilizes cyclodextran to inhibit oral plaque biofilm formation, reducing bacterial reservoirs linked to malodour and gingival inflammation. Suitable for toothpaste and mouthwash formulations, it aims for long-term freshness without harsh chemicals.
Overview
BIOFILM BARRIER™ is an innovative technology developed to enhance oral health by targeting the root cause of plaque accumulation. Utilizing cyclodextran, this solution inhibits the formation of biofilms that are responsible for maintaining bacterial reservoirs in the mouth. This not only reduces unpleasant odours but also helps in preventing gingival inflammation, ensuring long-term oral freshness. Unlike traditional methods that rely on bactericidal agents, BIOFILM BARRIER™ offers a prevention-led approach, making it a safe choice for daily use in products like toothpaste and alcohol-free mouthwash.
Technical specifications
Key features:
- Cyclodextran-based inhibition: Targets biofilm formation pathways, effectively reducing plaque build-up.
- Non-bactericidal action: Maintains oral health by preventing biofilm formation rather than killing bacteria.
- Compatibility: Designed for integration into everyday oral hygiene products such as toothpaste and mouthwash.
- Mechanistic support: Inhibits key enzymes involved in the biofilm and glucan formation, crucial for plaque development.
Technology readiness level
BIOFILM BARRIER™ is currently at Technology Readiness Level 3. Recent studies have validated the cyclodextran's efficacy in inhibiting biofilm-related pathways, and the technology is poised for further validation through bench screening, followed by prototype testing in toothpaste and rinse formulations, and upcoming 4–12 week clinical trials.
About Sarvotham Care Ltd
Sarvotham Care Limited is an established Contract Development and Manufacturing Organization (CDMO) and Contract Manufacturing Organization (CMO) that provides comprehensive end-to-end solutions for the healthcare, personal care, and home care industries. The company manages the full product lifecycle, including formulation research and development, clinical and pre-clinical services, and commercial-scale manufacturing. Its manufacturing capabilities span various dosage forms, such as granules, powders, tablets, capsules, liquids, creams, and gels. Sarvotham emphasizes technology-driven processes, regulatory compliance, and international quality standards, supported by internal laboratories equipped for advanced microbiological and chemical analysis.
The company serves as a strategic partner to multinational corporations and large Indian firms, focusing on on-time delivery and consistent quality. By offering private label services, Sarvotham enables clients to develop and market their own branded products while leveraging the company's manufacturing expertise and R&D infrastructure. Committed to sustainability and professional integrity, Sarvotham integrates environment, health, and safety (EHS) protocols into its operations, striving to meet both local and global market demands through scalable and innovative manufacturing solutions.
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