Biomimetic hair-liquid interaction analysis using QCM-D

Technology
Conceptual
University

A novel platform using QCM-D with biomimetic surfaces to study hair-liquid interactions, simulating various hair conditions for enhanced cosmetic R&D.

Overview

The proposed solution is a cutting-edge platform that employs Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) to study hair-liquid interactions using biomimetic surfaces. By mimicking the hair's complex surface characteristics such as lipid layers and damage conditions, this system provides cosmetic researchers with a precise, controlled environment to evaluate ingredient adsorption, penetration, and wash-off behavior. This technology facilitates a better understanding of how various treatments and environmental conditions impact hair, aiding in the development of improved cosmetic products.

Technical specifications
  • Biomimetic surfaces: Utilizes thiol chemistry to emulate 18-methyleicosanoic acid for healthy hair and sulfonate groups for damaged hair.
  • QCM-D system: Allows for real-time monitoring of molecular interactions including adsorption, retention, and desorption.
  • Environmental simulation: Incorporates humidity, temperature, and UV exposure controls to replicate realistic conditions.
  • Temporal dynamics analysis: Capable of simulating the effects of cumulative product use over time.
  • Data correlation: Provides insights by correlating QCM-D findings with macroscopic properties of real hair fibers.
Technology readiness level

The current development stage of this technology is at TRL 3, indicating that it has been shown to work in a controlled environment, with further validation necessary to advance to more practical and widespread applications.


About Universidade Estadual de Campinas

Universidade Estadual de Campinas (Unicamp) is a comprehensive public research university in Campinas, São Paulo, recognized for high research intensity and strong graduate education. Industry engages through an on‑campus science and technology park with co‑located corporate R&D suites and shared core facilities. Clinical translation is enabled by an integrated teaching hospital and specialized centers, while proximity to the Campinas–São Paulo innovation corridor makes onsite collaboration and talent access straightforward. Research is supported by state and federal agencies such as FAPESP, CNPq, CAPES, and FINEP, alongside industry contracts. A dedicated technology transfer office manages IP, licensing, and startup formation, and offers clear pathways for NDAs, sponsored research, and scale‑up.

Halo home
Partner smarter. Move faster.
Get new partnering requests
delivered to your inbox.