Carbohydrate-based salt taste reduction technology for reduced-sodium food products

Technology
Conceptual
University

A food science solution that uses tasteless carbohydrate oligomers to reduce perceived saltiness without lowering actual sodium content. By modulating ion chemical activity, these GRAS-approved carbohydrate-salt mixtures mask salty taste, enabling significant sodium reduction in food products while maintaining flavor.

Overview

This technology addresses the global challenge of reducing dietary sodium by using tasteless carbohydrate oligomers to mask salty taste perception. The solution enables food manufacturers to produce reduced-sodium products without sacrificing flavor, helping meet public health goals for lower salt consumption. The approach is grounded in the discovery that carbohydrates in solution modify the chemical activity of sodium and potassium ions, effectively reducing perceived saltiness while maintaining the functional and preservative properties of salt.

The value proposition for food industry partners is significant: a straightforward ingredient-based approach to sodium reduction that does not rely on artificial flavor enhancers or potassium chloride substitutes, which often introduce off-flavors. By using GRAS-approved (Generally Recognized as Safe) tasteless carbohydrates at sub-threshold concentrations, manufacturers can reformulate products with less salt while preserving the taste profile consumers expect.

Technical specifications

Mechanism of action:

  • Carbohydrates preferentially interact with salt ions in solution, reducing the effective concentration of free sodium and potassium ions
  • This interaction masks ions from taste receptors on the tongue, diminishing perceived saltiness
  • The effect correlates directly with measurable changes in salt activity in solution

Key features:

  • Uses tasteless carbohydrate oligomers at concentrations below sensory perception thresholds
  • Compatible with GRAS-approved ingredients, simplifying regulatory approval
  • Validated for disaccharides including trehalose and glucose
  • Applicable to both sodium chloride and potassium chloride salt systems
  • Does not introduce sweet or bitter off-flavors when properly formulated

Validation methods employed:

  • Analytical and physicochemical characterization using osmometric measurements, densitometry, and index of refraction
  • Sensory evaluation panels to assess taste perception
  • Cell-based assays using HEK cells expressing sweet taste receptors
Technology readiness level

The technology has been validated through published peer-reviewed research demonstrating the relationship between carbohydrate-salt interactions and taste masking. Prior studies have confirmed the hypothesis for several disaccharides, with published evidence in Food Chemistry journal. The current research phase extends these findings to tasteless oligosaccharides specifically selected for food-grade applications. The collaborative research team combines expertise in solution physical chemistry, analytical chemistry, chemosensory science, and biotechnology, providing comprehensive validation capabilities. The technology is positioned for industry partnership to develop optimized formulations for specific food product categories.


About Hebrew University of Jerusalem

The Hebrew University of Jerusalem is a comprehensive public research university with multiple campuses in Jerusalem and an agricultural campus in Rehovot. Its integration with Hadassah’s university hospitals enables clinical studies, access to varied patient populations, and co‑located research that accelerates translation. Industry engagement runs through Yissum, the university’s tech‑transfer company, managing IP, licensing, startup creation, and sponsored research agreements. Research is supported by competitive national funding and international programs, including European Union frameworks.

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