Cold-active antifungals from polar bacteria for food preservation
Discover cold-active antifungals from Arctic bacteria to combat food spoilage fungi like Z. bailii. This innovative solution leverages unique polar microbes to develop antifungal agents suitable for the food industry, with applications in various food matrices.
Overview
Polar bacteria offer a unique source of antifungal agents due to their adaptation to extreme environments. This research focuses on identifying and developing cold-active antifungals from Arctic bacterial strains to combat food spoilage fungi. By targeting fungi such as Z. bailii, which poses significant challenges in food preservation, this study aims to enhance food safety and shelf life.
Technical specifications
- Screening Methodology: Utilizes a co-culture screening method to identify Arctic bacterial isolates with potent antifungal activity against priority food spoilage fungi.
- Genomic Analysis: Genomes of promising strains will be sequenced and screened for antifungal biosynthetic gene clusters using antiSMASH 7.0.
- Extract Production and Testing: Soluble extracts from promising isolates will be produced and tested for antifungal activity both in vitro and in various food matrices.
- Scale-up Potential: The feasibility of scaling up production and application in food systems will be assessed to ensure industrial relevance.
Technology readiness level
This technology is currently at TRL 4, indicating that it has been validated in a laboratory setting. Further development and industrial partnerships are required to advance the technology towards commercial application.
About McGill University
McGill University is a comprehensive public research university in Montréal, Québec, known for an international community and a research‑intensive culture. Faculty and industry collaborate through shared core facilities and co‑located labs across downtown and hospital sites, with integration into a major hospital system enabling clinical research and translation. Proximity to Montréal’s established industry clusters and a vibrant innovation district give companies access to talent, pilots, and testbeds. Research is supported by Canada’s Tri‑Agency and the Canada Foundation for Innovation, alongside provincial and philanthropic sources. A dedicated technology transfer office streamlines contracting and IP, supports licensing and sponsored research, and connects partners to startups and entrepreneurship resources.
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