Collagen-stimulating and antimicrobial wound healing peptides

Technology
In development
University

Innovative peptides and lipopeptides designed to enhance wound healing by stimulating collagen production and providing antimicrobial effects, validated in cell and rodent models. Seeking partnerships for further development and commercialization.

Overview

We present novel collagen-stimulating peptides and lipopeptides designed to revolutionize wound healing treatments. These molecules have demonstrated excellent capabilities in promoting collagen production and exhibiting antimicrobial properties. Tested in both cell and rodent models, they show significant potential for accelerating wound healing while reducing inflammation and preventing infections.

Technical specifications

Key features include:

  • Collagen-stimulation: Rationally designed pentapeptides that enhance collagen production in fibroblasts, crucial for effective wound healing.
  • Antimicrobial properties: Cationic peptides that exhibit robust activity against common pathogens like E.coli, S. aureus, and P. aeruginosa.
  • Anti-inflammatory effects: Reduction of inflammation through decreased nitrite production, essential for reducing complications in wound healing.

These peptides are designed with novel lipids and linkers, forming micelles that enhance their stability and efficacy.

Technology readiness level

Currently, the technology is at a TRL 4, having been validated in laboratory and rodent models. We are actively seeking partnerships to conduct safety and efficacy tests, aiming towards licensing and market launch. The development path is supported by expert advice and market research.


About University of Reading

The University of Reading is a public research university with a comprehensive academic profile and a collaborative, applied research culture. Industry engagement is anchored by Thames Valley Science Park, which provides wet and dry labs, incubators, and grow‑on facilities. Its location on the M4 corridor near London and Heathrow connects partners with the Thames Valley tech cluster and a deep talent pool, while Henley Business School delivers executive education for R&D teams. Research is supported by competitive funding from UK Research and Innovation councils and Innovate UK, with additional support from European programs. A dedicated technology transfer office supports IP strategy, licensing, spinouts, and flexible contracting.

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