Combiotic: plant-based antimicrobial and anti-inflammatory respiratory solution

Technology
In development
Company

Combiotic™ is a novel plant-based solution designed to enhance respiratory health. It offers antimicrobial and anti-inflammatory benefits through nasal spray, softgel, and nebulizer formats. Preclinical data show efficacy against WHO-priority pathogens, meeting OTC standards.

Overview

Combiotic™ is an innovative plant-based solution aimed at supporting upper respiratory health. It combines natural small molecules with inorganic salts to provide antimicrobial and anti-inflammatory effects. Designed for nasal and oral delivery, Combiotic™ offers solutions in the form of a nasal spray, oral softgel, and portable nebulizer, ensuring ease of use and rapid symptom relief. Preclinical studies indicate its potent efficacy against 12 WHO-priority respiratory pathogens, surpassing conventional treatments. The solution is backed by GLP-level biocompatibility, toxicity, and stability data, aligning with OTC regulatory requirements.

Technical specifications

Key features:

  • Synergistic combination of plant-based small molecules and inorganic salts
  • Available in nasal spray, oral softgel, and nebulizer formats
  • Targets sinus-related pathogens, biofilm, and inflammation
  • Demonstrates high tolerability and rapid symptom relief
  • Supported by third-party GLP-level safety and efficacy data

Applications:

  • Chronic sinusitis
  • Allergies
  • Exposure to airborne pollutants
Technology readiness level

Combiotic™ is currently at Technology Readiness Level 4, having demonstrated efficacy in preclinical settings. The next steps involve formulation optimization, regulatory preparation, and pilot-scale production, with plans to engage potential licensing and commercialization partners.


About COMBio

A spin-off from a computational biodiscovery research center (COMBio) at AIMST University in Malaysia. Founded by a team of microbiologists and bioinformaticians, it focuses on phage technology to reduce agricultural and food losses.

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