Comprehensive clinical trial protocols for enhanced athletic performance evaluation
This solution offers a unified clinical trial protocol for evaluating the effects of pre- and post-workout solutions on athletic performance, including measures of muscular power, endurance, cognition, and recovery. Conducted at the University of Exeter with advanced methodologies.
Overview
This comprehensive clinical trial protocol is designed to evaluate the effects of pre- and post-workout solutions on various aspects of athletic performance, including muscular power, endurance, cognition, and recovery. The trial combines steady-state endurance and dynamic resistance exercises to assess the efficacy of nutritional solutions in enhancing athletic performance. The trial aims to provide a holistic evaluation through a unified testing approach.
Technical specifications
- Pre-workout solutions: Includes electrolyte drinks with varying osmolalities, caffeine, b-alanine, polyphenols, carbohydrate, creatine, carnitine, CoA.
- Post-workout solutions: Composed of unique protein, amino acid, carbohydrate, and polyphenol formulations.
- Performance measures:
- Muscular power and endurance assessed through time trials and dynamic resistance exercises.
- Cognitive functions evaluated using the Stroop test and VAS for focus, alertness, and motivation.
- Cardiovascular function measured through heart rate, stroke volume, and blood flow.
- Recovery assessed via muscle protein synthesis, glycogen resynthesis, and VAS for overall recovery.
- Methodology: Involves amino acid tracer infusion, ultrasound blood flow analysis, muscle biopsy sampling, and arterial-venous difference measurements.
Technology readiness level
The trial is at Technology Readiness Level 9, indicating that it has been fully validated and is ready for operational deployment. The research will be conducted at the University of Exeter's Nutritional Physiology Research Unit, using state-of-the-art equipment and methodologies to ensure accuracy and reliability.
About University of Exeter
The University of Exeter is a comprehensive public research university and Russell Group member with campuses in Exeter and Cornwall, combining strong research with collaborative, industry‑facing engagement. Co‑located clinical and research space with regional NHS hospital partners at the Royal Devon and Exeter Hospital, supported by joint facilities and a shared research office, enables clinical translation and trials. The university is an active partner in Exeter Science Park, including a University Enterprise Zone, and maintains an on‑campus Innovation Centre that links faculty with startups and scaleups. A formal collaboration with the Met Office supports data‑ and model‑intensive work adjacent to the agency’s Exeter headquarters. Research is supported by national research councils and health research funders; a central business engagement and technology transfer office manages IP, licensing, consultancy, and Knowledge Transfer Partnerships.
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