Continuous release system for natural anti-plaque agents
Innovative continuous release technology for natural anti-plaque agents aims to improve oral health by ensuring prolonged retention and efficacy in preventing early gingivitis and periodontal disease.
Overview
The development of a continuous release system for natural anti-plaque agents offers an innovative solution for enhancing oral health. This technology addresses the challenge of ensuring prolonged retention and effectiveness of anti-plaque agents in the oral cavity. By utilizing naturally derived agents, this system promises efficacy in preventing early gingivitis and periodontal disease, while remaining within safety limits recommended for oral care products.
Technical specifications
The proposed solution leverages advanced drug delivery systems such as slow-release sol-gels and adhesives, alongside conventional delivery methods like toothpastes, mouthwashes, and sprays. The formulation process involves the use of natural extracts characterized for the presence of alkaloids, flavonoids, glycosides, phenolic groups, and tannins. This technology is supported by a robust testing framework, including pharmacokinetics, toxicology, and efficacy studies conducted in a nationally approved animal testing facility. The effectiveness of the agents is evaluated using biofilm regrowth tests, fluorescence-based plaque measurements, and salivary biomarkers.
Technology readiness level
Currently at Technology Readiness Level 4, this technology has undergone initial testing and validation in controlled environments. Ongoing and future validation plans include comprehensive animal testing for drug effects and efficacy, as well as clinical trials to assess plaque accumulation using validated clinical indices and advanced imaging techniques.
About JSS Academy of Higher Education and Research
JSS Academy of Higher Education and Research (JSS AHER), formerly known as JSS University, is a deemed-to-be university located in Mysuru, Karnataka, India. Established in 2008 under Section 3 of the UGC Act, it focuses on higher education and research in medical and health-related fields. The institution comprises several constituent colleges, including JSS Medical College, JSS Dental College & Hospital, and colleges of pharmacy in Mysuru and Ootacamund. Additionally, it has integrated departments such as the Faculty of Life Sciences and Health System Management Studies. JSS AHER is part of the broader JSS Mahavidyapeetha group of institutions and is recognized for its state-of-the-art infrastructure and commitment to value-based education.
The university serves students and researchers by providing a multidisciplinary learning environment that integrates teaching, innovation, and community service. It emphasizes research excellence through its Research Hub, which supports initiatives in basic medical sciences, drug discovery, and biotechnology, connecting faculty and scholars with academic and industry partners. By focusing on global standards and social responsibility, JSS AHER aims to prepare healthcare professionals and researchers to address complex health challenges. The institution has received recognition for its academic quality, including NAAC accreditation and international ratings, reflecting its dedication to quality education and scholarly advancement.
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