Covalent hair dyeing using near infrared irradiation

Technology
In development
University

Innovative hair dye technology utilizing near infrared light to covalently bond dye molecules to hair, ensuring long-lasting color with no odor. This method leverages a catalyst and a diazo moiety for effective attachment without dependency on cysteines.

Overview

This pioneering hair dye technology uses near infrared light to achieve covalent bonding of dye molecules to hair, resulting in durable, long-lasting color. By employing a diazo moiety and a specialized catalyst, the dye is covalently attached to hair proteins, ensuring the color remains vibrant even after rinsing. This method eliminates unpleasant odors and does not require the presence of cysteines, making it suitable for a wide range of hair types.

Technical specifications
  • Activation Method: Utilizes deep red and near infrared light (600-800 nm) to activate catalysts.
  • Dye Attachment: Incorporates aryl diazo functional groups for covalent bonding to hair proteins.
  • Formulation: Comprises a gel or cream with the functionalized dye and catalyst.
  • Application Process: Involves application of the formulation followed by irradiation with an appropriate light source.
  • Benefits: Long-lasting color retention, no odor, and effective on all hair types.
Technology readiness level

This technology is currently at TRL 5, with successful demonstration in relevant environments. The next steps include optimizing formulation for cost-effective scale-up and pursuing commercialization strategies.


About Columbia University

Columbia University is a comprehensive private research university in New York City, combining an Ivy League academic profile with globally engaged scholarship and professional education. Its integration with a major hospital system through Columbia University Irving Medical Center and NewYork-Presbyterian enables clinical collaboration, access to diverse patient populations, and regulated studies at scale. State-of-the-art laboratories and shared core facilities across the Morningside and Manhattanville campuses support co-located industry projects, while proximity to New York’s finance, media, and healthcare ecosystems streamlines talent pipelines and pilot deployments. Industry engages via sponsored research, affiliate programs, executive education, and convenings that connect faculty expertise with corporate R&D priorities. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, and DoD, alongside New York State and philanthropic sources. Columbia Technology Ventures provides IP management, licensing, startup support, and translational funding mechanisms that lower barriers to commercialization.

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