Dentalshield: microbiome-friendly biofilm control for improved gum health

Technology
In market
Company

DentalShield offers an innovative approach to oral care by using a microbiome-friendly mechanism to control dental plaque. This solution forms a biomimetic film on teeth, preventing bacterial adhesion and biofilm formation without disrupting the oral microbiome, ensuring effective plaque control and gum health.

Overview

DentalShield is a cutting-edge oral care solution designed to manage dental plaque through a unique microbiome-friendly approach. Derived from the marine bacterium Alteromonas sp., this fermentation-derived metabolite (EPS) forms a thin biomimetic film on tooth surfaces. Unlike traditional antimicrobial methods, DentalShield prevents early bacterial adhesion and biofilm formation without eliminating bacteria, thereby preserving the natural oral microbiome. This innovation offers a significant advancement in gum health by reducing dental plaque while maintaining microbial balance.

Technical specifications

Key features:

  • Utilizes a fermentation-derived metabolite from marine bacteria to control biofilm.
  • Forms a protective biomimetic film on teeth to prevent plaque without killing bacteria.
  • Demonstrated a reduction in dental plaque by 82.4% after first use with sustained effects over 28 days in clinical trials.
  • Compatible with standard toothpaste and mouthwash formulations, ensuring easy integration into existing oral care routines.
  • Proven to maintain microbiome diversity, avoiding common side effects of conventional antimicrobial treatments.
Technology readiness level

DentalShield has achieved Technology Readiness Level 8, having been validated in clinical settings with a structured plan for commercialization. Short-term validation involves sample distribution and initial evaluations, while mid-term efforts focus on formulation optimization and compatibility testing. Long-term plans include scale-up and industrial validation to support product launch.


About Lallemand

Lallemand is a global leader in the development, production, and marketing of yeast, bacteria, and specialty ingredients. The company specializes in fermentation-based solutions, leveraging decades of research to create high-quality, science-driven products. By utilizing expertise in yeast-based technology and precision fermentation, Lallemand produces a wide array of functional ingredients, including natural vanillin, probiotics, food enzymes, and specialized fermentation nutrients for microbial health and yield.

These solutions are essential to customers in sectors such as human health, nutrition, food and beverage, and animal care. By providing standardized, clinically studied ingredients and non-GMO, vegan-friendly fermentation media, Lallemand helps partners overcome complex manufacturing challenges and develop sustainable, value-added consumer products. Through its extensive global network of production plants and research facilities, the company supports innovation across industries ranging from plant-based foods to dietary supplements.

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