Dermagenesis pro: chronobiological tri-layer ingestible longevity platform

Conceptual
Company

DermaGenesis Pro is a pioneering tri-layer ingestible tablet designed to enhance longevity by delivering active compounds in a chronobiological sequence. This innovative platform targets senolytic clearance, mitochondrial support, and dermal repair, aligning with the body's natural repair cycles.

Overview

DermaGenesis Pro represents a breakthrough in the ingestible beauty and longevity market with its tri-layer tablet design. Unlike traditional products that deliver active ingredients simultaneously, DermaGenesis Pro sequentially releases compounds in a manner that aligns with the body's natural repair cycles. The first layer targets senolytic clearance, the second supports mitochondrial function, and the third sustains dermal repair overnight. This approach addresses 11 of the 12 recognized aging hallmarks.

Technical specifications
  • Layer 1 (Immediate, 0–1.5hr): Contains Fisetin, Curcumin, Quercetin, Resveratrol, NMN, NR, Berberine, TA-65 for senolytic clearance and NAD+ activation.
  • Layer 2 (Delayed, 2hr): Includes Catalase, CoQ10, L-Tyrosine, Copper, PQQ for pigmentation recovery and mitochondrial support.
  • Layer 3 (Extended, 12–16hr): Comprises marine and bovine collagen peptides, Glycine, Proline, Hydroxyproline, Vitamin C, Zinc, Hyaluronic Acid for sustained dermal repair.
  • The formula utilizes GRAS-status ingredients and is supported by AI-directed computational ADMET/PBPK modeling.
  • Patent pending for its unique delivery mechanism.
Technology readiness level

DermaGenesis Pro is currently at TRL 3–4, with formulation architecture and computational validation complete. The next phase involves bench validation to further mitigate risks before progressing to large-scale trials.

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