Tejhana Consulting LLP

Dual-release sleep formulation for enhanced nocturnal recovery

Technology
In development
Company

A novel dual-release sleep formulation designed to improve sleep onset and maintenance while minimizing next-day grogginess. This formulation uses an immediate-release phase for rapid sleep initiation and a delayed-release phase to support sleep continuity. It aims to provide an effective, non-habit-forming solution for occasional sleep disturbances, improving sleep quality and next-day alertness.

Overview

This innovative sleep formulation is engineered to optimize nocturnal recovery and enhance daytime functioning. By leveraging a dual-release mechanism, the formulation targets both rapid sleep onset and sustained sleep maintenance, addressing common challenges faced by adults with occasional sleeplessness. The product is designed to align with natural circadian rhythms, providing a scientifically grounded approach to improving sleep quality without the side effects of next-day drowsiness.

Technical specifications
  • Immediate-release phase: Facilitates rapid onset of sleep
  • Delayed-release phase: Supports sleep continuity throughout the night
  • Dual-phase microencapsulation system: Ensures timed ingredient delivery aligned with natural sleep physiology
  • Objective sleep assessments: Includes actigraphy, sleep efficiency, total sleep time, heart rate variability, and psychomotor vigilance testing
  • Subjective measures: Evaluates sleep quality, alertness, and morning grogginess
Technology readiness level

This sleep formulation is currently at TRL 6, indicating that it has been demonstrated in a relevant environment, with ongoing validation through a randomized, double-blind, placebo-controlled study. The aim is to establish an evidence-based, non-habit-forming solution for sleep disturbances, paving the way for commercialization and broader application.

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