Dynamic microbioreactor for scalable peptide production

Technology
In development
University

A cutting-edge microbioreactor using continuous flow technology for scalable extracellular peptide production, offering enhanced yields and reduced media consumption through optimized environmental control.

Overview

This innovative microbioreactor employs continuous flow technology to enable scalable extracellular peptide production with enhanced yields and reduced media consumption. Leveraging precise microenvironmental control, this solution is designed to support various cell types such as adherent cells and yeast, optimizing the fermentation process. By utilizing real-time monitoring, this system ensures high purity and efficient peptide synthesis.

Technical specifications

Key features:

  • Continuous Flow System: Ensures scalable peptide production with enhanced yields
  • Microenvironmental Control: Optimizes conditions for diverse cell types, including adherent cells and yeast
  • Material Construction: Made from PDMS for gas exchange and transparency, facilitating real-time monitoring
  • Real-Time Monitoring: Allows for dynamic adjustment of parameters to optimize growth and peptide production
  • Scalability: Designed for increased volumes, assessing efficiency, yield, and purity at larger scales
Technology readiness level

This microbioreactor platform is at Technology Readiness Level 6, having been validated in relevant environments with a focus on optimizing culture conditions, process control, and scalability.


About Florida International University

Florida International University is a large public research university serving the Miami metro region with a comprehensive academic and professional portfolio and a partnership‑driven profile. Industry engages via a dedicated Engineering Center and full‑scale testing infrastructure, including the NSF‑NHERI Wall of Wind, enabling lab‑to‑field validation and custom testing, plus the market access that comes with Miami’s global gateway. Clinical translation is supported by FIU Health’s partnership with Baptist Health, while StartUP FIU connects companies to incubators, accelerators, and tailored innovation programs. Research is coordinated through the Office of Research & Economic Development and shared core facilities, with technology transfer managed by the Office of Technology Management and Commercialization.

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