Al-Hikmah University, Ilorin

Eco-friendly seed treatment for fvtox1 inactivation in soybeans

Technology
In development
Company

This solution provides an eco-friendly seed treatment for soybeans by using protease-rich plant extracts to neutralize the FvTox1 toxin, preventing Sudden Death Syndrome (SDS). It offers a sustainable approach with no risk of resistance or environmental persistence.

Overview

The proposed solution introduces an innovative, eco-friendly seed treatment for soybeans aimed at neutralizing the FvTox1 toxin, which is responsible for Sudden Death Syndrome (SDS) in soybeans. By utilizing protease-rich plant extracts, this method offers a biodegradable and sustainable approach to managing SDS without the risk of the fungus developing resistance. The solution specifically targets the toxin rather than the fungus itself, ensuring environmental safety and reduced non-target effects.

Technical specifications
  • Protease-rich plant extracts: Used to isolate and characterize novel bioactive compounds capable of blocking FvTox1 interactions.
  • In vitro bioassay: Conducted to screen protease-rich extracts for bioactive compounds, followed by QSAR analysis and ADME property assessment to select the most effective lead compound.
  • Validation process: Includes solvent-solvent extraction, HPLC, and nuclear magnetic resonance analysis for compound identification and characterization.
  • Field experiments: Planned to evaluate inactivation potentials and check for phytotoxicity and non-target effects.
Technology readiness level

This solution is at Technology Readiness Level 6, indicating it has been demonstrated in relevant environments and is moving towards field validation. Future validation plans include extensive research and development over a period of 10 to 11 months to ensure effectiveness and safety.

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