Electrostatic spray-dried functional ingredients for weight-management nutrition

Technology
Conceptual
University

Innovative electrostatic spray drying (ESD) technology creates functional ingredients for weight management by preserving bioactive compounds and optimizing nutrient release. This method enhances flavor, satiety, and nutrient delivery with potential commercial scalability.

Overview

This solution leverages electrostatic spray drying (ESD) to produce innovative functional ingredients designed for weight management. By preserving the potency of bioactive compounds and volatile aromatics, ESD enables the co-encapsulation of proteins, BCAA concentrates, peptides, micronutrients, probiotics, and more in a single particle. These particles are engineered to optimize flavor release, enhance satiety, and improve nutrient delivery. The technology is particularly suitable for creating nutritional products that offer better taste and consumer satisfaction while supporting weight management goals.

Technical specifications
  • Electrostatic Spray Drying (ESD): Utilizes low-temperature, inert drying to preserve bioactives that conventional methods might damage.
  • Co-encapsulation: Combines multiple active ingredients, including proteins, peptides, and probiotics, enhancing their synergistic effects.
  • Core-shell Architecture: Features fast-release surfaces for aroma/taste and mucoadhesive or hydrogel shells for prolonged satiety.
  • Cyclodextrin Complexes: Mask off-notes and potential nausea, improving consumer experience.
  • Microgel/Pickering Fragments: Deliver creaminess and improve mouthfeel with minimal inclusion rates.
  • In-vitro and Preclinical Validation: Includes saliva/gastric dissolution tests, Caco-2 uptake studies, and sensory/satiety panels.
Technology readiness level

Currently at TRL 3, this technology has demonstrated experimental proof of concept through in-vitro and preliminary in-vivo tests. Future efforts will focus on further validation, scale-up, and consumer testing to pave the way for commercialization.


About Catholic University of Leuven (KU Leuven)

KU Leuven is a large comprehensive public research university in Leuven, Belgium, anchored by a major academic medical center and a broad multidisciplinary profile. Industry engages through co-located facilities and shared labs, including access to advanced cleanrooms and prototyping via imec’s Leuven campus. Integration with UZ Leuven supports clinical partnerships and data-rich trials, while research and technology parks around the city connect companies with faculty and student talent. Research is backed by competitive European and Belgian funding, including the European Commission and the Research Foundation – Flanders (FWO). KU Leuven Research & Development manages IP, licensing, and spin-off formation, offering standardized agreements and dedicated partnership managers.

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