Emulsified bicontinuous microemulsions for delivery of polar and apolar agents
Innovative bicontinuous microemulsions solubilize and deliver both polar and apolar agents with high efficiency. Composed of natural, biocompatible ingredients, these microemulsions offer stable, low-cost solutions for diverse applications.
Overview
Emulsified bicontinuous microemulsions are cutting-edge delivery systems capable of solubilizing and delivering both polar and apolar agents effectively. These microemulsions are nanoscale dispersions of oil and water, stabilized by surfactant monolayers. They are particularly efficient, achieving solubilization near 10% for various agents, including proteins and antiseptics like chlorhexidine. Comprising natural, biocompatible ingredients, these systems are cost-effective and environmentally friendly, making them ideal for applications in pharmaceuticals, cosmetics, and agriculture.
Technical specifications
Key features:
- Bicontinuous microemulsion systems: Utilize surfactant monolayers to stabilize oil and water dispersions.
- High solubilization efficiency: Capable of solubilizing agents at concentrations exceeding 5 wt% at room temperature.
- Natural and biocompatible: Composed of oils with antimicrobial properties, offering a safe and sustainable solution.
- Stability and versatility: Can be emulsified in water or oil, with maintained stability and storage capabilities.
The microemulsions will undergo rigorous testing for solubility and encapsulation efficiency, using techniques like small-angle x-ray scattering and dynamic light scattering to characterize the systems. Further investigations will focus on emulsion stability, release kinetics, and potential applications in atomization-based delivery systems.
Technology readiness level
This technology is currently at TRL 3, indicating an experimental proof-of-concept stage. Future validation plans include comprehensive testing of solubility, stability, and release kinetics, with an expected completion timeline of 18-24 months.
About University of Tennessee, Knoxville
UT offers a partnership model that reduces risk, accelerates time-to-value, and supports long-term growth strategies for industry—providing an attractive platform for companies seeking to formalize collaboration and establish a long-term presence in the East Tennessee region. By aligning institutional investment with regional and national priorities, UT provides a stable and effective platform for industry collaboration, technology deployment, and sustained economic impact.
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